I believe their capsules are enteric coated. I’ve had demonstrable benefit from their Neprinol (natto-, serratipeotudase and amla).
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Their Neprinol page does state that it’s in an acid-resistance capsule (in the “FAQS” section). The page for Nattovena page doesn’t say anything similar. 
I’d be interested in hearing more about the benefits that you observed with Neprinol. I might try it after my course of Nattovena.
I’ve been taking 35+ supplements twice a day for at least 2 years. I do not take rapa yet but I am looking at it.
I’ve been taking 4,000FU twice per day for a total of 8,000FU/day (DoubleWood nattokinase) for over a year and starting in 2024 started taking 6,000FU twice per day for a total of 12,000FU/day.
I’ve run no tests before or after. I asked for a CAC and Drs said no so far. Had an aortic valve replacement and 3-way bypass in late 2017.
I am trying to do everything that I can to extend my life and get my cardiovascular disease under control.
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About sixteen years ago a carotid scan was pretty bad (3/5 Framingham quintile but 5-years risk). I did nine months of Neprinol 3x3/day in empty stomach and a course of EDTA -IV. My lipids are genetically bad to boot. After that period redid scan and there was a nearly zero score. Three more months doing Neprinol 3x1/ day, it was then zero. I now do annual 30-day Neprinol of 3x1/day. Last carotid scan about 2 years ago and was completely clean and heart scan was in the teens total and no particular bad spots. This year I switched to cyclodextrin on account of a PRP injection that I didn’t want to interfere with (rotator cuff tear). Hope that helps. I’ll look into where I heard about coating.
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The positive natto studies I’ve seen mention that 2,000FU is too low a dose to get any significant results. You need at least 8,000FU, and the optimum number in one study was 10,800FU. So this negative study doesn’t tell us much. It reminds me of the negative Vitamin D studies where participants were given 2000IU (and in some cases even less) and found no benefit (Duh!)
Exactly right! Natto needs to be at the higher dose that you mention.
FWIW I have stated before, I take{for the past 4 months] 15,000FU to 24,000FU everyday.
Each softgel capsule is 3000FU
Using , photo of the label
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