Any Alternatives to Grapefruit Juice

[RufusDawes]

There is a GF shortage right now, it’s getting hard to find and prices are $7 per half gallon in my area… are there any alternatives to GF when taking Rap to increase bio-availability?

[A_User]

Worth to keep in mind:

Grapefruit associated with increase in all-cause mortality

Learning about drug metabolism, P450 system is used to detoxify toxic substances in the liver, so I wondered if grapefruit are harmful on its own, and there is an association, but it could be because it affects drug metabolism, or other residual confounding. When compared with non-consumers, frequent consumers of red wine, tea, peppers, blueberries and strawberries were at reduced risk of all-cause mortality (P<0·05), with the strongest associations observed for red wine and tea; multivariable-adjusted hazard ratios 0·60 (95 % CI 0·49, 0·74) and 0·73 (95 % CI 0·65, 0·83), respectively. Conversely, frequent grapefruit consumers were at increased risk of all-cause mortality, compared with their non-grapefruit consuming counterparts (P<0·05). [image] Considering threads like this: Rapamycin and Grapefruit Juice Grapefruit interaction with longevity meds? Grapefruit Extract vs Grapefruit Juice for Increased BioAvailability? and that Brian Kennedy has wondered that it could incre…

[Beth]

I was told not to consume my pomegranate supplement the day of taking rapa because of the multiplier effect.

I don’t know how it compares to gf.