Out of curiosity did you notice the good/benefits everyone seems to tout when their T goes up (on treatment)? Never done T treatment before and wondering what to expect.
No, the bad outweighed the good. But there are guys on here who thrive at 800 ng or higher. Because I am slightly built, I suspect that it is easier for me to reach T overload.
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While a handful of labs might synthesize this compound for research purposes, pharmaceutical companies generally steer clear of it due to the risks associated with human consumption.
The CHMP noted that although the studies showed an increase in testosterone levels with EnCyzix,
they did not look at whether EnCyzix would improve symptoms such as bone strength, weight gain,
impotence and libido. In addition, there is a risk of venous thromboembolism (problems due to the
formation of blood clots in the veins) with the medicine. Therefore, the CHMP was of the opinion that
the benefits of EnCyzix did not outweigh its risks and recommended that it be refused marketing
authorisation.
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Iāve had testosterone far higher than what he reported and feel great on it.
Enclomiphene will be different to TRT, Iāve seen guys get weird emotionally on enclomiphene.
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What do you mean by āslightly builtā? Also can you post your full before and after hormone blood test?
Dang, Iām a bit emotional by nature (one of traits I dislike LOL) and definitely donāt need that. Anyway, I started Enclomiphene four days ago at 12.5mg/day and canāt say anything about T numbers obviously but I can definitely tell the difference, i.e. last four days woke up with morningwood lol(used to be 1-2 times weekly prior, and not every day) and for some weird reason I feel that joint pain is gone, used to have a lingering one in my left knee and would let me know every time Iād do squats and it disappeared literally the first day I took eclomiphene. donāt know if anyone has ever reported such, but thought was worth mentioning. No side effects other than first day had a medium headache which didnāt come back the second day and onwards.
If you notice weird negative emotions long term on this consider TRT instead and compare the two.
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My stack is similar including the drugs, but a bit less extensive:
rapa, pitavastatin, exetimibe, brenzavvy, omega3 (4:1), tongkat ali, pure encapsulations ONE multi, taurine, lithium orotate, DHEA, tongkat ali, taurine, urolithin A, creatine
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I will. I would have gone TRT right away, but I donāt like the idea of having to do it for rest of my life though. If nothing else, itās such a chore to maintain especially when travelling and such. Plus having to give blood and watch markers etcā¦Iāll see how it goes but I might have to anyway (at some point).
Btw, while it is early Iām also seeing other positive things in way of losing a bit of weight about 1.5 lbs in a week or so, and not feeling bloated. Since nothing else has changed I think that is the other positive of the Enclomiphene. As far as emotions, I might seem a bit easier to get upset if that counts, but nothing major Iād say.
Anyway, do you mind expanding a bit on benefits you felt (are feeling) when you started TRT and do they continue (or it is a one-shot deal when you start) and how much you do weekly and what else you do to counter any sides (if applicable). You can dm me if you donāt like sharing it publicly. much appreciated.
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Iām 5ā7" and 130 lbs.
Itās not a one shot deal, it builds up over time. Itās like a 2nd puberty basically.nGenerally gets better and better as you continue it.
Improved muscle building, better mood, improved libido, more motivated, better socially, and likely more.
Havenāt really had any sides, but I do TRT as a healthspan intervention among many longevity interventions like tirzepatide, Rapamycin, Telmisartan and more which I believe offset potential negatives of TRT.
I donāt see myself going without it, life is a lot better this way.
I think for people who are overweight with a bad metabolism a good ancillary medicine is tirzepatide (or maybe retatrutide, but Iāve never used that)
Being overweight means more adipose tissue which means more aromatase enzyme activity which means more testosterone to estrogen conversion which can be an issue for some men. I am against the use of aromatase inhibitor drugs for most circumstances as they produce unfavorable effects.
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yes, it is Doxycycline.
Enclomiphene can raise T, Free T, E2, LH, and FSH. If SHBG is high there may not be much of a rise in Free T and as a result no benefit when taking Enclomiphene. If E2 is high to the point of being above range after taking Enclomiphene I suspect that could be a cause for being more emotional and potentially leading to gynecomastia. Blood testing all of these before starting Enclomiphene and again a few weeks later could be helpful.
As some have noted Enclomiphene (enclomiphene citrate), not clomiphene (clomiphene citrate brand name Clomid) is what men should use.
If enclomiphene raises T, but not Free T because of high SHBG the solution is TRT treatment. However, TRT treatment generally shuts down the bodyās normal production of T. To prevent that taking Enclomiphene with TRT can help the body continue producing itās own T because enclomiphene raises LH and FSH which stimulate T production. To get a combination like this I suspect the logical route would be an enlightened doctor, a specialty clinic or an online specialty clinic.
Oh, and one more thing, from what Iāve read TRT treatment alone using injections may lead to some hair loss.
I am not a doctor, but I believe this is correct.
Boron may be able to lower SHBG, also Proviron.
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I take a similar stack as you, and will make a post soon. Are you taking Test / Deca / HCG daily, or is that a weekly average. Outside of the HCG (I can see the case for ED or EOD), what are the benefits of taking ED vs 2-3 times per week (less arromitizaion)?
I was taking them all daily. However, I since changed my stack a little and now I do 500iu HCG 3x per week instead. I was mixing testosterone and nandrolone in the same syringe for daily shots although I since dropped nandrolone because my hematocrit got too high for my liking.
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Yeah. I added an SLGT2i to my stack a month ago and know I need to watch Hemocrit closely. What was the number you were triggering off of that was too high? And did you donate blood at all?
HCG - are you taking those doses it to replicate natural hormones? Or maintain fertility? I am doing 250 EOD but donāt care from a fertility standpoint.
I donāt want to disclose in public here but it was high
The HCG is to get my testicle size back to normal after years of shutdown.
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Here is my current stack:
| Name | Dose | Purpose |
|---|---|---|
| Telmisartan | 20mg | BP |
| Tirzepatide | 2.5mg/wk | Metabolic/weight |
| HCG | 250 IU EOD | TRT adjunct (testicular) |
| Ezetimibe | 10mg | ApoB < 50 |
| Rapamycin | 6mg Every 4-8 Weeks | Longevity |
| Tadalafil | 2.5mg | Vascular/endothelial + urinary |
| Brenzavvy (bexagliflozin) | 20mg | Longevity (Heart / Kidney Support) |
| Testosterone Cypionate | 150mg/wk (Split 2x a week) | Free-T (high SHBG) |
| Trazodone | 50mg (as needed, not daily) | Recovery bridge |
| Acarbose | 25mg / meal | Blood Sugar |
| HGH | 2 iu (daily) | Sleep / Recovery |
| Nandrolone | 50-75 mg / week | Experimental: Joint Pain Management / Recovery (HCT Being monitored) |
| Pitavastatin | 1mg | ApoB < 50 |
| Name | Dose | Purpose |
|---|---|---|
| Glycine | 3g | Sleep |
| NAC | 1200mg | Hepatic/glutathione |
| Omega-3 | 3-4g | Lipids/inflammation |
| TMG | 1g | Homocysteine |
| Magnesium (SlowMag, Citrate and Threonate) | ~340-390mg/day | Sleep/cognitive/CNS/recovery + general repletion |
| Zinc glycinate | 30mg | Sleep |
| Thorne Basic Nutrients 2/Day | 2 caps | Mutti-vitamin |
| Creatine | 5g | Strength |
| Vitamin C | 500mg | Antioxidant; collagen synthesis cofactor |
| Collagen Peptide | 10g | Connective tissue / joint / tendon support |
| B12 (methylcobalamin) | 1000mcg | Methylation |
| B2 (riboflavin) | 100mg | MTHFR cofactor |
| Vitamin D3 + K2 | D/K2 only (very low dose) | D status |
| Flonase | std | Nasal/RERA |
| Astaxanthin | 12 mg | Antioxidant; skin/UV, eye, and mitochondrial support |
| Ca-AKG | 1g | Longevity candidate |
| Lithium Orotate | 2 mg | Low-dose neuroprotection/mood |
| Nattokinase | 12000 FU | Fibrinolytic / cardiovascular (clot/circulation support) |
| Ubiquinol | 200mg | CoQ10/mitochondrial support; statin-induced CoQ10 depletion offset (aware there is little evidence of this and may be dropped) |
Overall, pre-SLGT2i my blood sugar / insulin, etc. was excellent (A1c - 5 and Fasting Insulin - 2.5%). My eFGR and kidney markers are not optimal and I am using it as an insurance policy. I am going to see if its possible to lower dosage of SLGT2i ā not because of side effects, but just looking for lowest effective dose. My lipids (pre-statin, ezetimibe) were also OK-ish ApoB 65-75. However I am taking the lowest possible dose in order to get ApoB < 50 (ideally 30-40).
No side effects with any of the pharma listed. I added Nandrolone to help with some joint issues, but am going to really monitor blood work / hemocrit. I donate blood about every 60-90 days as well.
I exercise daily. Lift 4-5 days a week, and do 180-220 mins of zone 2, and 40 minutes of zone 4/5 a week. Plus walking a dog 30-50 mins a day (~9-10k steps on average)
Roughly ~10-12%bf, and caloric maintenance for me is about ~3,000 calories a day.
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I think that is an excellent stack. Not much to criticize; of course, some of the items are particular to your needs, but not for everyone. Are you able to get tadalafil in 2.5 mg tablets, or are you cutting the 5 mg ones in half?
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