Where to buy transcutol in the uk

green246 · October 30, 2023, 8:27pm

I am trying to make my own cream and i am finding it virtualy impossible to find transcutol in the uk. could someone help pls thanks

RapAdmin · October 30, 2023, 8:37pm

I’m not sure about the UK, but the EU, here is a source, and some other details and naming that may help you search:

Can you use water instead of Transcutol when making Sirolimus cream?

No - water will not work. Transcutol is available in EU, bought from here: https://www.laboratoriumdiscounter.nl . And perhaps other places. Transcutol has a number of different chemical names/identifiers. Here is a list: 2-(2-Ethoxyethoxy)ethanol: Ethoxydiglycol, 3,6-dioxa-1-octanol, DEGEE, diethylene glycol monoethyl ether, Carbitol, Carbitol Cellosolve, Transcutol, Dioxitol, Polysolv DE, Dowanal DE Chemical Identifier: CAS Number 111-90-0 Examples of Where you can order / buy Transcutol from in the USA: LotionCrafters: Transcutol / Ethoxydiglycol Laballey.com : Transcutol / Diethylene Glycol Monoethyl Ether Some people use DMSO, but its a more powerful solvent, perhaps more than you want (but diluted, it may be fine, I have not used it topically): just a little information I saw recently in a book on cosmetic dermatology that covered the excipients like transcutol and DMSO. See the bold comment on DMSO below. Here is an excerpt: “Penetration enhancers In this sec…

J0hn · October 30, 2023, 9:11pm

I live in the UK and I bought mine off Amazon

https://www.amazon.co.uk/Eastchemlab®Diethylene-glycol-monoethyl-ether-CAS/dp/B08BRL8K36

It’s a bit pricey at £79.99/500g and there are only 3 left in stock

J0hn · October 30, 2023, 9:22pm

I used to work with DMSO and it’s a very good skin penetrator. It also used to penetrate our latex gloves with no problem (this was in the days before nitrile gloves). Spill a drop on your hand and you can taste it in your mouth in minutes. At the end of the day my friends used to complain of the garlic-like smell emanating from my skin.
Personally I wouldn’t use it on a daily basis.

World_Traveler · October 31, 2023, 1:50am

I bought Propylene Glycol on Amazon.es for a big bottle. 21euros. It is used extensively in cosmetics in EU. Have had excellent results. I use 1 0z. to dissolve rapa before mixing with 300 grams Cetaphil cream.