Matt Kaeberline, Peter Attia… keep reminding us that there is NO EVIDENCE that isocaloric TRE (Time Restricted Eating) has any Longevity benefits.
But then I read this interview of Rozalyn Anderson where she says that animals DO LIVE LONGER : Rozalyn Anderson Explains Caloric Restriction | Lifespan.io
"An interesting finding emerged – the pair-fed animals got their food in one meal, ate it within hours, and had no food until the next day. They were effectively time-restricted eating, unintentionally. They lived longer than ad libitum mice despite having the same amount of food. Studies since then have shown the fasting component contributes to lifespan extension with CR: the maximum benefit comes from fasting plus calorie reduction, but you can get some benefits just from fasting.
There’s not a lot of clarity on the effect size of time-restricted feeding, but you’re saying it does help?
Time-restricted feeding is a reasonable paradigm. When you look at all the evidence from caloric restriction, fasting, time-restricted feeding, and alternate-day eating across species – from yeast to flies to worms to mice to monkeys to people – it’s compelling. The fasting component is hugely beneficial.