I don’t know anyone who has even heard of Rapamycin in my circles. My very supportive doc was like “wow, seriously, you want to take this”.
We follow the US when it comes to drug approval or emerging medical dogma…we are a rubber stamp. We don’t stick our necks out.
Thats equally true down here in the US, even in San Francisco, except if you stray into the biotech communities.
How do you make topical from rapamycin? Would love to make some. Thanks for your formula.
Details on topical rapamycin here: Rapamycin for Hair Growth and Pigmentation, Skin Anti-aging
and here: DIY Rapamycin skin cream
Do you have a formula for DIY Rapamycin cream/liquid for hair growth? Thanks so much!
Here is what one forum member is doing: Rapamycin for Hair Growth and Pigmentation, Skin Anti-aging - #26 by Agetron
Yes, I am getting lots of new hair growth. It is slow because the new hairs are coming out of dormant hair follicles. Very fine and thin, but resilient. The new hairs are thickening my front and crown hair.
@RapGuy . @RapAdmin , others!:
Do you have lab results with/without grapefruit?
Do you have lab results with generic pills/ pfizer pills?
What is the concentration we should aim? (The log graph presented at the top of the chat is a real mess). I guess the only useful part is after 24 hrs. Am I right to say that one should expect concentrations of 2ng/mL after 24 hours? (I’m following the line of 3 mg/m2. This because for my weight (72kg) and my height (179cm) gives an approximate superficial area of 1.9m2. Then 3mg/m2 equates to 6mg total for me.
Do you have the raw numbers of that graph for the first 24 hours? As I said, it is useful in the range 0-24hrs.
Many. many thanks! (I’m still looking for a GP that can prescribe me the lab tests in Perth Australia, this is another mess!)
For full transparency, I work at Marek Health.
We offer low-margin self-service blood testing as part of our mission to reduce the barrier of entry to affordable health care.
Our Rapamycin (Sirolimus) serum blood test (LC/MS-MS) via LabCorp is only $59 vs $95 at LEF.
Additionally, the LEF “Chemistry Panel” (Lipids, CBC, CMP) is only $25 at Marek vs $35 at LEF.
Also, Marek Health offers the high sensitivity CRP test for $20 vs $42 at LEF.
And the IGF-1 test for $39 vs $75 at LEF.
You can find links to the aforementioned tests here: Rapamycin related blood tests - JustPaste.it
If this is against the rules here please delete my post. I stand to gain nothing, I am simply trying to help others get access to the same lab tests at lower costs.
This is helpful information - thanks for posting.
This type of service you are offering seems high value and helpful to our audience.
Hey Mike,
Great questions!
You do not need to pay any consulting fee to access lab tests.
If you want interpretation, coaching, and prescriptions, that is when you would pay a $250 patient exam fee.
Marek Health has two lines of business:
I’m going to be fully transparent here.
The self-service lab work is not a profit centre for us. It’s goal is to get people access to affordable diagnostic lab work as we believe it’s important. However, it also serves as a free marketing campaign for our brand. We believe if we offer the most affordable, convenient diagnostic lab tests it is inevitable that a huge number of eyes utilize our services. A small percentage of those will read the about marek page, or follow our social media, or read our trustpilot reviews and decide they want help interpreting their lab markers, opimizing their health, improving their longevity, etc and that drives business to our real profit centre – guided optimization.
Hence, the lab test prices you see are not introductory prices or special sales prices. They are simply lab tests with very low margins, mostly to cover overhead.
I noticed Marek offers the new Glutathione test through Labcorp for $59. Other places charge at least twice that. Glynac (NAC + glycine) is reputed to improve glutathione levels. It would be interesting to see if anyone has a measurable increase in glutathione after being on this mix for a while.
Where do you get the lab test for trough serum Rapamycin levels? I’d like to test mine.
Thanks
I think most people are using LEF or Marek Health. The latter costs less. Here is a link.
Both of these companies use Labcorp. You can find out if there’s a nearby lab at this link.
In some areas you may only have Quest Diagnostics. In that case, you could use Ulta Labs. It’s more expensive: Sirolimus, LC/MS/MS | Ulta Lab Tests
You can look for nearby Quest Diagnostics locations here.
When you order labs yourself, they’re pre-paid and not through insurance. NY, NJ, and RI restrict self testing.
Thank you, much appreciated!
Why am I not surprised you had a long post on this? Thanks!
Wondering who is your doctor?
I do not understand why your RDW would be a bio marker of any value and would help lower your bio age by 13 years. It is the Red Cell Distribution Width, affected chiefly or solely by your iron stores. Little use beyond that clinically. But Your obviously well read and invested in the process (I am 63 as well) so curious of your thoughts.
I disagree, RDW is used as an epigenetic age marker on many age calculators because there are many, many papers citing RDW as a risk factor.
The paper below is just one example.
“RDW levels above the median were associated with a significantly lower survival rate on long-term follow-up”
“Higher RDW levels at discharge were associated with a worse long-term outcome, regardless of haemoglobin levels and anaemia status.”
https://onlinelibrary.wiley.com/doi/full/10.1093/eurjhf/hfp109