It has been a while since Vince Giuliano has posted to his blog. For those not familiar with Vince, he is a 93 year old with a broad science background. He does in-depth analysis of longevity related topics. And I find his personal health habits interesting and relevant.
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Thanks for that. I’ve read all of his blogs religiously and consider Vince to be an extremely smart guy and an expert on all things aging. He tends to keep a low profile, avoids hyperbole, and is very evidence based.
Regarding some of his points:
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I agree that loss of epigenetic information and the subsequent loss of beneficial gene expression is a major cause of aging. On the other hand, I’m not as confident that the present day tests are all that reliable.
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I fully agree that chronic inflammation plays a huge role in the process.
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It does seem that 122 is our max age limit at present, but we’re fairly close to overcoming it.
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He mentions rapamycin, but as far as I can tell, he doesn’t take it himself. He doesn’t respond to emails so I’m not certain.
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He mentions metformin as a life extender in the same sentence as rapamycin and I certainly disagree.
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He’s taken numerous supplements over the years. At one count it was about 60 a day. He’s still going strong.
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He makes an interesting point that if you want to be a healthy 200, you must first do the things required to be a healthy 100.
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I’m looking forward to his educational material. I wish that he were a part of this forum.
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Thank you for the reference. Excellent article and it gives me hope to live to 120 yrs at least.
“In particular, I have focused on the importance of controlling chronic inflammation for healthy aging”
Fortunately, I gleaned the importance of chronic inflammation many years ago and started using anti-inflammation supplements such as Boswellia serrata (Frankincense).
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Jeanne Calment made history when she died at the age of 122 in 1997, but a new investigation claims her daughter actually assumed her identity in 1934. Was the World’s Oldest Person Ever Actually Her 99-Year-Old Daughter? Where are we getting the 120?
My great Aunt passed away at 106. I recall; she was a first-generation Sicilian living in the US, my grandfather’s sister; in fact, all his siblings (6 of them) lived well into their late 90s. She lived with her husband, that smoked two packs a day; she was a beautician into her 80s worked with hair dyes and chemicals. Her favorite meal was a burger, fries, and a shake, which she ate daily! Genetics! Can’t imagine if she took Rapa, and had a diet and exercise routine, maybe 120?
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| 1 | Kane Tanaka[4] | F | 2 January 1903 | 19 April 2022 | 119 years, 107 days | Fukuoka | Fukuoka |
|---|---|---|---|---|---|---|---|
| 2 | Nabi Tajima[4] | F | 4 August 1900 | 21 April 2018 | 117 years, 260 days | Kagoshima | Kagoshima |
| 3 | Chiyo Miyako[4] | F | 2 May 1901 | 22 July 2018 | 117 years, 81 days | Wakayama | Kanagawa |
| 4 | Misao Okawa[4] | F | 5 March 1898 | 1 April 2015 | 117 years, 27 days | ĹŚsaka | ĹŚsaka |
| 5 | Tane Ikai[5] | F | 18 January 1879 | 12 July 1995 | 116 years, 175 days | Aichi | Aichi |
Full list below; verified by the Gerontology Research Group, based in LA, CA.
List of Japanese supercentenarians - Wikipedia.
Andrei Gudkov also opines that the cliff (as he calls it) is 120 years.
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Boswellia is good.
You can keep the myrrh.
Send the gold to me!