In a study published today (October 19) in Science Advances, researchers report that they have temporarily delayed or reversed some of these age-related changes in mice using extracellular vesicles (EVs) derived from younger animals’ stem cells. Just two weeks of treatment increased older mice’s physical strength, triggered signs of regeneration in several tissues, and reduced certain organs’ biological age as measured by epigenetic biomarkers.
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Full Open Access Paper:
Small extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice