https://x.com/EricTopol/status/1871588943155912887
https://www.nature.com/articles/s41551-024-01311-6
I’m pretty sure I have slightly impaired glucose tolerance even though I have reasonable hemoglobin A1C values (my diet is still far healthier than most people), so this might figure it out even though no doctor will tell me I have any problem.
What’s your HOMA-IR? With a CGM, do you ever go above 140 mg/dL?
Very interesting. This has opened my eyes to more complexity in blood sugar dysregulation. I will study this further to better understand my own physiology better.
“ Lifestyle interventions such as weight loss and exercise reduce insulin resistance, whereas reducing dietary sugar and glycemic load might benefit those with β-cell deficiency and/or incretin deficits; metformin reduces hepatic glucose production, acarbose prevents absorption of dietary carbohydrates in the small intestine, thiazolidenediones are powerful insulin sensitizers, and GLP-1 agonists augment β-cell insulin secretion and reverse insulin resistance via weight loss.”
