A gene therapy that instructs cells to produce more of an anti-ageing protein called klotho is about to be offered by a US company at overseas clinics to bypass FDA rules
An injectable gene therapy that promises to make people live longer will soon become available in certain nations. This is despite the fact that it hasn’t been tested in rigorous clinical trials and doesn’t have approval from the US Food and Drug Administration (FDA) or other major regulators.
The gene therapy, developed by Minicircle – a company headquartered in Austin, Texas – is designed to make cells produce more of an anti-ageing protein called klotho. To get around the extensive clinical testing required by the FDA to approve a therapeutic product in the US, Minicircle will offer the largely untested gene therapy to those willing to travel to Honduras, the Bahamas or Panama. The company has opened a waitlist on its website and says it will make the treatment available in the next six months.
I misunderstood the follistatin treatment. I thought it was permanent. It only lasts about a year, and the Klotho also only lasts about a year. And they can kill it with the antibiotic if it doesn’t agree with you. Of course who can afford it, right? But I guess if you can then this is not crazy. Very exciting. I’ll wait a bit and see what happens.
I know a couple of the 24 people who participated in MiniCircle’s “proof of concept” trial and had positive results in terms of energy levels and strength. To my knowledge, none has had a significant adverse reaction. The people I know only wish that the effect had lasted longer. (It is short-term - 6-12 months - because the circular DNA injected into abdominal fat cells doesn’t last.) My personal hope is that MiniCircle will be able to offer this therapy in certain U.S. states, at least to certain patients (with incurable but not-yet-terminal diagnoses), thanks to recently-passed state-level “Right to Try 2.0” laws.
Hope its cheap and lasts forever. My Klotho-1, daily injection of 100-300mcg costs just $300/mo at 150mcg. Only available via a private $200/mo health coaching group. But anyone can join. TPC ARMY
BUT FWIW I don’t feel any benefit, as I didn’t feel any benefit from 10B exosomes locally injected etc. Or the embelical cord stem cells… Glad others report feeling benefits from the gene therapy et al!!
I don’t have any problem not feeling benefits. Our bodies are unique and we are on a path of experimentation and some will be useful some not.