Good day folks. Quick recap: I stopped rapa months ago after developing slight swelling on my left cheek which was due to a very rare condition that has been linked to rapamycin (essentially the rapamycin caused a build up of a particular protein). It usually resolves when ceasing rapa. It has not for me but has decreased somewhat and only I really notice anything now, given we are generally our own worst critics.
I switched to acarbose (50mg two-three times a day dependning on frequency of my meals…on it for past 10 weeks or so) and apart from the widely reported flatulence, its been well tolerated.
I do wonder though, given I do not wish to give up on the mTor inhibitor route entirely, if the everolimus analog might be a better option given its shorter half life. Could this-in theory-lead to a better side effect profile if one does NOT increase the dosage to compensate?