Has anyone had success buying quality Trazodone from an Indian supply for sleep. It’s only available for pets in Australia or perhaps compounded. Any suggested suppliers or brands?
You can buy trazodone from (Maulik Parekh maulik7@gmail.com) and many others, but not from Jagdish Nikose.
I bought some a few years ago from India, but I don’t remember which brand.
The typical price should be ~Trazodone 50 mg 300 pills $ 30.
Shop around if someone wants to charge much more than this.
You can go to IndiaMart and look at the different brands offered, and then you can ask for a quote for the brand you like from Maulik.
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)I bought 100 50 mg tabs of Trazodone from Maulik for $10 US. It seemed to work the same as the product I bought in Canada with a prescription.
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I bought traz from Maulik in Nov; same price, $10 for 100-50mg. I’m in the US.
does it suppress glymphatic waste clearance?
i have some spares but idk if I ever need to use them
FWIW: OpenEvidence says: "No, there is no evidence that taking trazodone as a sleep aid suppresses glymphatic waste clearance during sleep.
The glymphatic system is responsible for clearing waste products from the brain, and its activity is known to increase during sleep. However, the specific impact of trazodone on glymphatic clearance has not been directly studied in the provided references.
The references discuss the role of sleep in glymphatic clearance and the potential modulation of this system through various interventions, but they do not address the effects of trazodone specifically. For example, one study explores the enhancement of glymphatic clearance through sensory and pharmacological modulation of sleep physiology, but it does not mention trazodone.[1] Another study investigates sleep-related changes in brain microstructure and glymphatic clearance using diffusion imaging, but it focuses on zolpidem, not trazodone.[2] Additionally, a study on brain clearance during sleep and anesthesia does not provide information on trazodone’s effects.[3]
Therefore, while sleep itself is crucial for glymphatic clearance, the specific impact of trazodone on this process remains unclear based on the current literature. Further research would be needed to determine if trazodone has any significant effect on glymphatic waste clearance during sleep."
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