I came upon this article which sparked my interest in the association between inflammation as a potential driver of the general symptoms we associate with aging: pain, increased inflammatory markers, liver dysfunction, etc. Perhaps you can provide additional insight and opinion on therapeutics.
Some of the drugs used in the treatment of Crohns seem likely candidates for biohacking intervention, such as infliximab and vedolizumab which have specific effects on TNF-α. What do you think or what other paths of intervention do you think would be of interest in real clinical application?