Thymus rejuvenation, TRIIM-X, Fahy - HGH daily shots. One year later! See it for yourself - My Thymus money shot!

Bear with me, I haven’t created a new topic for some time, typically sharing and adding to existing topics. But, I didn’t want this update to get lost in the sea of replies. SO… here it is a stand alone topic.

Thymus rejuvenation. Fascinating - but really!?! This Fahy dude was researching a dried up gland nobody cared about for youthful rejuvenation, T-cell formation and overall immunity health, skin quality , organ repair - SPARE ME the snake oil salesman!

But then… I really became interested in the Thymus when Matt Kaeberlein @mkaeberlein interviewed Dr. Greg Fahy over a year ago. Link: https://www.youtube.com/watch?v=Xj45rcfzrbM
Matt Kaeberlein was intrigued enough at the end of his podcast to consider trying it - a let’s go!

So… why not me? Chatted with my Personal Physician January 2025 - showed him the Fahy TRIIM research. He was aware of a few other patients doing well on it. He said he would support me - but pharma grade HGH was expensive ($2,000-$3,000 per month - ouch!). Our buddy @AgentSmith helped me find top HGH at about $110 per month for 3-4 iu daily injection. Ordered my hooch. Tested my IGF-1 (measured at 490) had the good stuff. Took my shots daily.

A year later, I start checking on how to see my thymus.Ultrasound - can’t see through the bone, MRI - okay but not great. CT-Scan the Gold Standard.

Okay, I did not do a baseline CT-Scan, assuming my thymus would be like everyone elses - dried up and full of adipose tissue - FAT!! A CT-Chest Scan costs $8,000 - after insurance - you pay $2,000 not cheap and there is the radiation factor for the test. So, I only did a final scan. In the Matt Kaeberlein interview it was shared that the thymus under rapamycin would repair some and be compacted - actually smaller - tighter. A brief exchange of PM messages from me to Matt K. determined a 3-month wash out of rapamycin prior to the CT-Scan would give my thymus ample opportunity to reach its full size. TBH - quitting rapamycin for 3-months after 4 years straight weekly use was hard. At 2 months I was really feeling funky, return of some arthritis, gym workouts a bit harder. Kind of in a funk. Happy to say I have been 2 months back on rapamycin and rocking again.

Then, this timely article came out: Long Dismissed in Adult Health, the Thymus May Be Critical for Longevity and Cancer Treatment | Mass General Brigham

Let’s compare a healthy thymus on the left image in the article to a less healthy thymus on the right.

Use the above image as a reference – I did not outline my thymus - it shape is pretty obvious.Click to increase size and detals. Excellent scan.
And now my thymus at the top - pic 25/67 and one layer down - cutting through it… pic 26/67 - it is big, full and fat free.

So there you are… now only using small HGH dose of 2 iu for maintenance every other day, a bit more when I feel skin damage or other body trauma needs a kick. Next to rapamycin – HGH is the best addition to my healthspan plan followed by TRT. In this order, Rapa, HGH, and TRT. I think all three are rocking me.

I will be 68 years in 2 weeks. Feeling like 40’s again.

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:muscle: Love it!!!

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Hey Matt - your Optispan interview with Dr. Fahy was amazing - I have probably heard it no less than 10 times!

You both were way ahead of the curve. Now look – Link: Long Dismissed in Adult Health, the Thymus May Be Critical for Longevity and Cancer Treatment | Mass General Brigham

I hope your HGH Journey has gone well. Appreciate all your support and answers to my questions! Every journey on the road for me – starts with an Optispan interview. Truth!

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The most interesting man in the world!

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My #1 Rapa Fan – Joseph-the-Man!
Thank you!

Great experiment and contribution to the community @Agetron

Thanks for putting in the effort and funds to provide this information. I’m glad I was useful with respect to sourcing. And as every enhanced gymbro has known for years, cheap Chinese HGH works! Glad to see that your thymus is thriving.

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Bud - thanks - But, I could never have done this experiement without your help on locating HGH sources online. Months of your labor and I just had to click on a link. Instant options at a great price. I used 3 of your sources in all… every one paid out in aces! Fantastic help.

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I am bit mystified by the $8000 CT chest scan price quoted by OP : That may be the price that insurance gets billed. However the cash price (without insurance) for a CT chest scan in San Diego is $300 (without contrast) or $360 (with contrast).

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Is HGH oral, patch or injection?

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490 IGF1 is an amazing response for this dose!
Look at mine, but I’m at 15UI right now
I guess mine is fat free too lol

Thanks for sharing your results!

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It is an injection. Oral or patch hgh doesn’t exist.

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Yes - quite the range it seems.

  • A computed tomography (CT) scan is a painless, noninvasive diagnostic test used to create views of structures inside the body.
  • The average price of a CT scan can be anywhere from $300 to $6,750. However, your cost will depend on many factors, including the place of service and body area scanned.
  • Some health plans may cover authorized CT scans. However, you may still have out-of-pocket costs such as copays, coinsurance, or deductibles.
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Exactly. You get the HGH powder in a vaccumed sealed vial - reconstitute (can be 10 or 24 units) it with bacteriostatic water and inject your dose with a diabetic - small needle.

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Amazing results and you look amazing too! thank you for sharing your journey and results.

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Transdermal application is possibly.

One paper below there are more.

Article

“Sustained transdermal delivery of human growth hormone from niosomal gel: in vitro and in vivo studies”

https://www.tandfonline.com/doi/full/10.1080/09205063.2022.2045667

My thinking is applying on top / around the thyroid.

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Also FWIW…

AI-generated answer. Please verify critical facts.

Research into microneedle patches for human growth hormone (HGH) has demonstrated that transdermal delivery via dissolving or coated microneedles can achieve pharmacokinetics and bioavailability similar to traditional subcutaneous injections, offering a painless, needle-free alternative for self-administration. Silk-based and titanium microneedle systems have shown the ability to maintain HGH stability and release the hormone over sustained periods (up to 7 days or more) without requiring cold chain storage, while eliminating the risk of sharps waste.

However, commercially available patches fall into two distinct categories with different mechanisms and levels of clinical validation:

  • Clinical-Grade Microneedle Patches : Scientific studies (e.g., Acta Pharmaceutica Sinica B , 2023; Nature Materials , 2025) describe patches using actively separated or dissolving microneedles to deliver recombinant human growth hormone (rhGH) or somatropin directly into the bloodstream, showing efficacy in animal models for treating growth hormone deficiency.
  • Supplement/Homeopathic Patches : Products like ISOTROPIN-HGH or HGH Power Patch often contain homeopathic dilutions (e.g., 2C/30C), amino acid secretagogues (arginine, lysine), or claim to deliver high doses of somatropin (e.g., 75mg) that lack the rigorous clinical trial data supporting the efficacy of medical-grade microneedle systems.

Key distinctions between these approaches include:

Feature Microneedle Research Patches Commercial Supplement Patches
Delivery Mechanism Physical penetration (microneedles) Passive diffusion or secretagogue stimulation
Active Ingredient Recombinant Human Growth Hormone (rhGH) Homeopathic dilutions, amino acids, or claimed synthetic HGH
Clinical Evidence Validated in preclinical animal studies (rats, guinea pigs) Limited to manufacturer claims; no major clinical trials cited
Regulatory Status Investigational / Medical Device Sold as dietary supplements

While bioinspired patches mimicking natural HGH secretion rhythms have shown promise in promoting bone growth in mice and rats, the widespread medical adoption of HGH patches is currently limited to research settings, whereas consumer products often rely on unverified claims regarding dosage and absorption efficiency.

AI-generated answer. Please verify critical facts.

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A low-dose amino acid supplement (SeroVital®, Sanmedica International, LLC, Salt Lake City, UT) containing 2.9 g of supplemented L-lysine, L-arginine, oxo-proline, N-acetyl-l-cysteine, L-glutamine, and schizonepeta was developed based on the stimulatory effects of some amino acids on hGH release.

Shizonepeta is Jing jie in Chinese medicine.

The increase in hGH 120 minutes following administration of the amino acid supplement represented a 682% or 8-fold increase from baseline (Table 1, Figure 1). The area under the curve for hGH from time 0 to 120 minutes (AUC0-120 min) was also significantly greater following treatment with the amino acid supplement compared to placebo (Table 1).

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I was a volunteer subject in the TRIIM-XA trial, in the very first cohort, continuing for 18 months. I just want to point out that the protocol Agetron has followed is pretty different from the protocol that Dr. Fahy and Intervene Immune have followed in their work with volunteers. First, we never took HGH daily - the doses were less frequent than this, and the dose amounts were adjusted frequently, based on blood test results. Second, we took Metformin and DHEA throughout the study, aiming to counteract some of the ill effects of HGH, notably raising Insulin and possibly Insulin resistance. See for example https://diabetesjournals.org/care/article/35/4/768/38342/The-Association-Between-IGF-I-and-Insulin. It does look to me like Agetron has seen thymus regrowth as well as muscle growth, much as seen in the TRIIM-X studies. But IMO there are some risks to be aware of for anyone taking growth hormone, especially for a lengthy period. I would definitely be getting blood tests fairly often, looking for IGF-1 and Insulin changes, as well as CBC and CMP information.

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Did you target a certain igf1 level/z-score ? How often did you test your levels?

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I can only discuss my personal results, but over time my blood tests have shown IGF-1 in the middle of the reference range (100-110 in the range 34-245 ng/mL), and a Z score also in the middle (-0.1 to +0.3 in the range -2.0 to +2.0 SD). My insulin level has stayed well below the high end of the reference range (8 to 9 in the range <= 18.4 uIU/mL). During TRIIM-XA, we were getting blood tests almost once a month; presently I think every 3 months to 6 months for most tests is sufficient.

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