The probiotics I make, as stated in my posting.
Make a 1 quart of what I call cream yogurt,
A quart of light cream added two scoops of organic inulin powder from chicory root mix well then added one shot{2.7oz/90ml] of Yakult, place in water bath at 100°F set for 24 hours this is my probiotic.
Slightly off topic, but do we have any definitive study that shows that probiotics taken orally do anything? I suspect that the stomach acid would destroy the active ingredients. I can see why a fecal transparent or perhaps a probiotic suppository would be effective, but the idea is unpleasant.
As this seems to be a Senolytic therapy, maybe the Mayo clinic could weigh in as they are the leaders on Senolytic research. Dr. Kirkland is in charge of the Fisetin project.
His research seems to have stalled though, so it seems that Fisetin is a bust.
Theoretically such senolytic therapy looks promising but the possibility to completely ruin gut Microbiome sounds alarming to me. I just finished my course of doxy in connection with a viral infection (not Covid) that I recently contracted. It was prescribed with the purpose of preventing possible pneumonia taking into consideration my history with rapamycin. It apparently worked, I did not develop pneumonia. However, doxy definitely negatively affected my Microbiome and I feel it and try hard to restore friendly bacteria lost. It’s easy to wipe it out but difficult to repopulate it. I feel the negative consequences of doxy on all levels. And it’s not good.
Lara, could you elaborate a bit about your lingering symptoms from the dox? I am concerned that my microbiome could be all messed up and present no symptoms at all. Perhaps some day I might be diagnosed with parkinsons out of the blue due to some intestinal microbes that I did not even know were there.
This is the scary thing about all of these interventions–we have so few biomarkers to track. We think Rapamycin must benefit the microbiome, or be at worst neutral, but there is nothing to measure.
Ray, I had a pretty unusual viral infection. 3 tests for Covid showed negative. The exact virus has never been diagnosed. The infection affected only my head: hearing, vision ( got double vision for 2 days), scalp pain, headaches, very poor sleep, brain fog. There was a suspicion that I may start pneumonia and 2 antibiotics were prescribed preventively. One of them was doxy. Pneumonia never developed, but infection soon resolved with some residual affects, which I blame on antibiotics, but could be mistaken. My digestive system reacted in a way that I could not eat anything without having problems with horrible bloating, constipation, diarrhea, burning, pains, etc. (never had anything like it before.). It also produced a pretty unusual tremor inside of my whole body, similar to what ppl experience when low on sugar. It all eventually improved, but my digestive tract doesn’t feel the same. I take different probiotics, drink yogurt and kefir, but it still feels like a long way to recovery. Horribly affected my energy too. I literally force myself to walk couple miles a day. Unfortunately, it’s difficult to know what to blame: a virus or 2 antibiotics that I took. My doc doesn’t have any answers for me. I was on rapamycin during the whole course of disease.
Sorry to hear that! Are you drinking store bought kefir or making your own? I’d recommend the latter if you think your microbiome got nuked. It’s much more powerful than whatever you get at the store.
Thanks. I make my own kefir. It’s gradually getting better.
Question about this protocol: is there any suggestion of doing it more than once? Seems like it’s the kind of thing that could be repeated two, three times a year or so.
It’s interesting how they are using Vit C here. It’s NOT acting as an antioxidant but rather as a stress source. I’ve read in the past that mitochondria can use Vit C in the absence of oxygen (very inefficiently) - perhaps that’s related?
In the patent application once yearly was mentioned.
What was your dose of doxy, compared to the 100 mg twice a day in the breast cancer study?
It is easy to test some principal types of gut bacteria before and after an intervention.
It was the same: 100 mg twice daily.
I recommend eating probiotics when starting the three-drug combination therapy. Posted on this on the thread “My DAV therapy begins”.
Was that a 2 week course?
No, just 1 week course.
Wow so many cancer curing compounds!
https://www.onscope.com/ipowner/en/owner/ip/4119477-lunella-biotech-inc.html
Michael Lisanti and his wife are leading researchers of cancer stem cells, cancer metabolism, tumor recurrence and metastasis, drug resistance…
And? I was just remarking on the remarkable long list of different compounds that cure or totally prevent cancer. Can’t wait for a thread to be started for each and every one.
Under witch circumstances and at what age would you start? If there aren’t so many risks, it could make sense to start intermittent courses early.
My personal problem is a lot of stress. This causes inflammation and damaged cells.
