The Road to Rejuvenation (UCSF)

A good article covering active research at UCSF related to Klotho, hypoxia, inflammation, stem cells and caloric restriction.

Fortified stem cells. Enhanced memory. A longevity hormone. UCSF researchers are finding out whether we can cancel – or at least delay – old age.

When laboratory mice are born – pink, with their eyes shut tight – they’ve already begun to age. In about eight days, their gray-black fur starts to show. By two months, the mice are grown up but young – their coats full and shiny, their bodies slender. Like humans, they reach a natural, physical peak.

This stage doesn’t last long. They lose the ability to reproduce by their first birthday. By age 2, mice are considered older adults – the rough equivalent of 70 human years. They’re filling out in the middle. Their fur is dull and flecked with white.

But they’re not too old to change. If researchers give them a running wheel or cut their calorie intake, the mice become healthier and more energetic. The researchers aren’t particularly surprised; we have long known that certain habits are beneficial to aging bodies, including our own.

Now researchers want to understand why – and they’re making fascinating discoveries that could transform human aging and tackle a host of ailments, from heart disease to dementia. At UC San Francisco’s new Bakar Aging Research Institute (BARI), 70 scientists and clinicians are all trying to answer the same question: How can we slow, or even reverse, aging?

Full article:

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An article further down the page explains why rapamycin.news is the happiest place on earth. People with lower body temperatures have better moods than those with higher temperatures. We established some time back that rapamycin lowers body temperature. I noticed that twice during covid. When my temperature was taken on entering a building, it was about 97 both times.

Doing my taxes right now. I don’t understand why some people consider it an unwelcome chore.

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If that is the way you think, we will seldom see eye to eye. :laughing:

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Maybe it reminds him how much money he made last year? :slight_smile:

Or maybe he’s a true optimist? :slight_smile: :slight_smile:

Argonaut, are you using a tax software package or just a calculator and a pencil ! I’m trying to get a handle on just how much fun you’re having with this!

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While we’re on the subject - if we beat death, does that mean we won’t have to pay taxes either?

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Some people have already beaten taxes. Probably the same people who have the best chance to beat death too.

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