Taken together, our study introduces a unique and efficient model for large-scale antiaging drug screening in vertebrates and suggests sapanisertib as a potential therapeutic option for treating premature aging and promoting healthy aging.
Paywalled paper:
Establishment and application of a zebrafish model of Werner syndrome identifies sapanisertib as a potential antiaging drug
https://www.pnas.org/doi/10.1073/pnas.2413719122
Source: https://x.com/davidasinclair/status/1895939773455614448
https://www.ecfr.gov/current/title-21/chapter-I/subchapter-D/part-300/subpart-B/section-300.50