Kidney Doctor Reveals: How Your Gut Bacteria Affects Kidney disease
IgA Nephropathy(most common primary renal disease worldwide) is purported to be the key pathology that highlights the pathophysiologic significance of gut-kidney axis.
It is no accident that GALT (gut assiciated lymphoid tissue) repsresent whopping 70-80% of the entire immune cellular army deployed along the gut lining due to the gut’s constant exposure to food, microbes, and other antigens, requiring robust immune surveillance and regulation. Enterocytes die and renew every 7 days; with such high turn over, it is by design that surveillance has gotta be of extraordinary quality and quantity.
As an aside, Enteric Nervous System of nearly 500 million neuron(more than spinal cord) and the entire gut microbiome (considered to be more than rest of the body’s biomass).
Yeah, a lot is packed inside the gut!
No wonder, you gotta go with gut feeling!
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