I had a doctor a while ago recommend either antihistamine or anti-inflammatory drug for reversal of gray hair. I don’t remember which one. I never tried it because at the time I was very anti-pharmaceutical.
As for puffiness in under eye area, I have heard anecdotal claims of hGH being effective at reducing this. Unsure how this compares to growth hormone releasing peptides like the ones I think I recall you saying you’ve tried.
Excellent podcast… with a keen sense of dick humor. Good to know tadalafil is the best option.
Thanks to my urologist been on tadalafil for 4 years daily. Huge benefits. Hahaha.
Glad the thread is back on topic. I think it’s a wonder drug IMO. Since I last posted here in February, I’ve been taking 2.5mg/day and it definitely makes a difference. My average SBP is down 3-5 mmHg. It definitely helps with pumps in the gym - doing isolation movements like biceps curls can induce painful pumps. Penis is more consistently “alert” - my wife walks in with a nice perfume and he wakes up quickly.
I’ve never had prostate problems, but the urologist on Attia was saying he prescribed 2.5-5mg/day for patients with hypertrophy, and it was massively helpful.
I also don’t believe there is any dependence issue.
And mechanistically, it makes sense. Peripheral vasodilation should be reducing overall burden placed on the heart during rest times. There are a few studies out there that higher doses, particularly of viagra, might have anabolic effects and improve hypertrophy with training, likely driven by the better blood flow to muscles.