Systemic extracellular acidification is a hallmark of aging

And what do we eat to become more alkaline?

The word starts with C.

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If only I could get a lot more citrate without overwhelming my kidneys (swollen ankles)…with a ton of sodium. Is the key just to build up slowly?

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I think building up slowly is best. All of this is not that easy as there are balancing factors. In the end efficient mitochondria as what we need.

You do need to monitor the effects and manage renal load in the round.

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This “Alkaline” in diet / systemically is not new.

FWIW…

The above paper above has 53 reference’s to get you started on your quest.

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There are many advocates of a small daily dose of baking soda.
Do you think this is a possible solution for age-related acidification?

Some samples:
“Kidney disease: A daily dose of sodium bicarbonate can help people whose kidneys can no longer remove enough acid from their blood.”

“While no scientific studies have found that baking soda cures cancer, research does show that it can help some cancer treatments work better. Some chemotherapy drugs need alkaline conditions. Others become more toxic in an acid environment. That’s why some doctors suggest using some form of sodium bicarbonate for best treatment results. Your oncologist can tell you if your drugs will get a boost from baking soda.”

“Some studies show that baking soda helps you perform longer at your peak, especially during anaerobic exercises or high intensity training and sprinting.”

"Baking soda may help delay fatigue due to its high pH, letting you perform at max intensity for longer.

For example, one study found that cyclists who took baking soda exercised for an average of 4.5 minutes longer than those who didn’t take baking soda."

Etc., etc.,

My most recent labs measured carbon dioxide at 28 nmol/L, and the note showed that was at the high end of the reference range.

Am I to believe this might actually be a positive signal rather than a potentially troubling one?

I cannot say on that. Much that at times my urine is quite alkaline (pH 9) I would not think serum has moved that much.

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