eg
Against the completed rescue/support Boltz runs in this workspace, the ranking was roughly compound 38 > compound 30 > carnosic acid > EGCG > quercetin > honokiol > TH10785 > sulforaphane > curcumin > eugenol > ferulic acid > rosmarinic acid > gallic acid. So the best tradeoffs are:
- Best cheap screen: quercetin
- Best serious buy-now OGG1 activator: TH10785
- Best custom quote targets for something like Onepot Flow: compound 30, compound 38, and probably compound F from the older rescue paper (2018 rescue paper); for compound F I could not confirm a current catalog source, but it looks simpler than 30/38, so custom synthesis is likely more straightforward
and for defective asian NQO1*2
automated chemical synthesis might be moving fast! [tho the most general form is allegedly harder than bacterial synthesis of peptides]
eg https://chemrxiv.org/doi/pdf/10.26434/chemrxiv-2025-x508x