Supplemental alkaline phosphatase targets the gut barrier to prevent aging

Don’t know enough but your blood test might be different from what you want in your micro biome

See et this

Anyone have any experience on whether the peptide BPC157 might help ALP with fighting leaky gut?

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You’re sure about this? My recent result was 40 and flagged as LOW. I read deficiencies in magnesium and/or zinc could cause that, even though I consume plenty of both.

I’m not a doctor. I read about this in Michael Lustgarten’s excellent book “Microbial Burden and what you can do about it”. I’m sure the microbial burden is not the only thing that affects AP. Google lists protein deficiency and a couple diseases as well. If these things are ruled out then that leaves really good news about your microbial burden.

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Update, I asked him and this was his response

“< 48 for ALP is associated with lowest all-cause mortality risk, so you’re likely good there

Liver enzymes and risk of all-cause mortality in general populations: a systematic review and meta-analysis - PubMed

So thank you for bringing it to my attention @Bicep . I’m not so worried anymore

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Have you tried supplementing with these? It looks like one of the safest approaches right now in terms of longevity.

I was hoping someone had tried with available current IALP: