Sirolimus now available at TrumpRx dot gov ($0.66/mg)

90 1 mg tabs for $68 in my area.

Hope this helps everyone who is taking it.

Website: https://trumprx.gov

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Well, not everyone. From the Wikipedia entry:

Public opinion

A February 2026 YouGov survey found broad support for the new government website when it is not called TrumpRx: 57% approve and 19% disapprove. When the name TrumpRx is used, approval drops to 41% and disapproval rises to 31%. The name has the strongest negative effect among Democrats. Approval falls from 45% to 13% when TrumpRx is mentioned, and disapproval jumps from 27% to 62%. Independents show a similar pattern: approval drops from 49% to 21%, and opinions split evenly (31% approve, 31% disapprove) when the name is used. Republican support remains steady, with strong approval whether or not the name is cited (78% vs. 81%). Mentioning TrumpRx also reduces intended use overall: those “not at all likely” to use the site rise from 35% to 44%. Democrats’ reluctance increases sharply (50% to 74%), as does Independents’ (32% to 45%). Republicans, however, become more likely to use it when the name is mentioned, with “not at all likely” dropping from 23% to 15% and “very likely” rising from 9% to 20%. Overall, the name boosts Republican enthusiasm but lowers broader public support and usage.[31]

I’m not in the US but I’m just curious: how does this work? Your doctor gives you an off label rapamycin prescription and then you can buy via TrumpRx? How does this price compare to other sources?

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Yes, that is the idea. That price is pretty much the same price as India purchased. And you know it hasn’t sat in a 120 degree warehouse for months.

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That’s a fantastic price!

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I haven’t gone with a U.S. doc yet, largely because of the price. But with this price it makes sense to switch if I can find a doc for less than $400 a year, so quarterly “check in” ($100$) for refill, but I still have a year or 2 Indian supply on hand at 3dayx6mg once a month. Also I might have to convince the doc that the dosing is fine which is another wild card headache I’d rather avoid.

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Thanks for sharing. That’s a pretty competitive price compared to many other sources. More affordable access to sirolimus could be helpful for people who are already using it under medical supervision.

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Many online sites, push health was $65.00.

Look around not difficult to locate

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I use https://www.pushhealth.com/; the fee is $68 for Dr.'s Rx. Use either of the two discounts they have available for prescriptions. The current price is $123 for 90 2 mg tablets at CVS pharmacy. Same price as https://trumprx.gov/

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How do you know that?

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You don’t… In a positive or negative way… That’s the is issue. In the USA etc there are rules and regulations around drug supply chains, when you buy from grey market in India you don’t know how things are stored, etc

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CVS stores in San Diego refused to fill my RX for Rapamycin at the no insurance price quoted by Goodrx etc and said it can only be filled by CVS speciality pharmacy, an online division that normally handles expensive cancer drugs. In my case CVS Speciality insisted on billing my insurance and then told me I needed to have my doctor fill out an some insurance form but the link explaining details led nowhere and their phone number could provide no details. Others reported that their RX was filled by CVS speciality ( they had no insurance on file with CVS) demanding over $10 per mg and refusing any goodrx coupons.

I tried talking to a local CVS pharmacist who insisted they no longer stock Rapamycin, even though the online i nventiry on their website said otherwise.

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I have always bought mine at CVS (not specialty) with a Good RX coupon.

If CVS is no longer doing it, Target, through Good Labs, is the same price)

If you buy a year’s worth, it’s aprox .56 per pill.

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Hello again Beth,
May I ask how you get your prescription? I usually by from Maulik to avoid going through the prescription battle with docs, and I have had no problems (that I know of) with the quality of any of the drugs I get from him. The problem is the FDA at entry. How is everyone else here getting their prescription? I’m in Las Vegas.

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When was this? I got a rapa prescription filled at CVS in DM Heights, back in December 2024.

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I’m guessing you meant goodrx.

BTW, the free coupons are over at goodrx.

InsideRX offers ‘free’ coupons. Prices a tad higher than those shown on goodrx.

https://insiderx.com/drugs/sirolimus

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@none Ha, you are correct! I had Good labs on the brain because I placed an order with them this morning!
FWIW, yesterday, I just picked up a huge supply of two different prescriptions at CVS and they gave me the lowest Good RX price… and they never asked for the coupon details. Last year, when I placed my order for the year, I did sign up for one month of their preferred pricing.

Hi @Mdecrasto long time no see!
I get my rx’s from my internist. I wish I had a good name to share with you!

December 2025.

BTW here is the CVS RX inventory check but even when I go to stores in San Diego that show availability, the pharmacist will deny they have any availability as soon as they hear the name Sirolimus, without doing any actual check on their computer ! They immediately say it can only be filled by CVS Speciality (online only, but once filled, order can be picked up any any local CVS pharmacy).

Here is the list of drugs CVS says can only be filled at CVS Speciality (Rapamune is listed under Transplant on the last page), so at least the local CVS Pharmacist was right about officially only filling Rapamune RXs at CVS Speciality, but I wonder what happens to the remaining stock at the local Pharmacy.

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good luck getting a dr here to write you a script. I know mine wouldn’t

Here is a list of doctors that prescribe rapamycin for longevity: Rapamycin Prescription, Doctors that Prescribe It

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