Senolytics (Dasatinib / Quercetin) That Eliminate Senescent Cells in Human Fat Alleviate Signs of Diabetes

More good news for senolytic therapies:

For their study, Xu and colleagues investigated the effects of targeting P21high cells in mouse models, and tested the two drugs, dasatinib and quercetin, in animals carrying human adipose tissue transplants. Dasatinib and quercetin have previously been shown to extend lifespan and good health in aged mice. Moreover, the team noted, “Dasatinib plus quercetin (D+Q) has been shown to specifically kill senescent cells.” The fat tissue was donated by individuals with obesity, who were known to have metabolic problems.

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