Am taking.25mg semaglutide weekly for ckd stabilization about a year and half. HOWEVER, I have to stop for a few weeks every couple of months due to mental doldrums (blahs).
I tried taking mucuna pruriens .5g during my last break and just today without a GLP break. Fantastic and immediate results (despite a cloudy day in SoCal).
Anyone else tried this?
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Nice. Have not tried semaglutide but have tried mucuna.
I’ve had some good success with mucuna pruriens extract of 15% l-dopa, and use 400mg mucuna (60mg l-dopa) 1-3x a day.
One could also look into inhibiting various enzymes that breakdown dopamine for a possible greater effect 
I’ve also been experimenting, combining the mucuna with various products like creatine, lecithin (+ other stuff at times) to boost other neurotransmitters, aiming for a bigger effect on thinking, mood, energy etc.
All taken with a meal.
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I bought mucuna but haven’t had enough courage to try it. I opted for 10mg Vyvanse when I needed for demanding mental work as needed. Huberman says mucuna can be very strong if dose too much.
I upped my creatine which seems to help me to buffer stress better, anyone? It is also said it could help sleep quality.