By Duke-NUS Medical School
March 24, 2026
Researchers have identified a molecular mechanism that helps explain why exercise remains so effective in maintaining muscle health with age.
Scientists have identified a molecular switch that may help explain one of the biggest benefits of exercise as people grow older: the ability to keep muscles repairing themselves.
A research team at Duke-NUS Medical School, working with Singapore General Hospital and Cardiff University, found that physical activity can restore a key internal balance in aging muscle cells. Their results, published in the Proceedings of the National Academy of Sciences (PNAS), offer a clearer picture of why muscle strength declines with age and why exercise can help slow that process.
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