Scientists Have Reached a Key Milestone in Learning How to Reverse Aging

#1

The original press release;

Link to the Cell paper;

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#2

This paper also by David Sinclair

Says " A fate-tracing method for EpiSCs with DNA double-strand breaks (DSBs) was developed. EpiSCs with DSBs promptly differentiate to be selectively eliminated from the niche."

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#3

The paper you posted link to is almost 25 month old, published December 20, 2021.

The link to the paper on the current subject in the title was just published January 12, 2023

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#4

The paper I posted to has not been retracted. Hence there remains this question as to what happens with Double Strand Breaks.

The “information theory of aging” based round methylation does not explain all the known facts. (in particular it does not explain the parabiosis/something in the blood aspect.

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#5

Epigenetic information loss seems to be an important part of aging, though the hyberbolic headlines almost imply it is equivalent to aging. This could be a tremendous human therapy some day, helping us to live longer and healthier, but there will never be a single cure for aging.

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