NAD in some Charles brenner discussed this a lot
Apigenin/cd38 inhibitors
Too much cd38 in choroid plexus https://www.cell.com/neuron/fulltext/S0896-6273(26)00218-7?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627326002187%3Fshowall%3Dtrue&fbclid=IwVERDUAS7RgJleHRuA2FlbQIxMABzcnRjBmFwcF9pZAwzNTA2ODU1MzE3MjgAAR4nMehD3y0JyyLrLWU_Ohzvz-KmI8dlnLwd-Z4ds0jRXioBMcazhrXQv3EQdA_aem_LZB1Fj5X8ZFke-UG3kfsGQ