Findings In this cohort study including more than 356 052 participants in the UK Biobank, there were multiple modifiable and nonmodifiable risk factors for YOD. Alcohol use, higher formal education, and lower physical frailty (higher handgrip strength) were associated with lower risk of incidence of YOD, whereas increased risk of YOD was associated with low socioeconomic status, apolipoprotein E status, alcohol use disorder, social isolation, vitamin D deficiency, high C-reactive protein levels, hearing impairment, orthostatic hypotension, stroke, diabetes, heart disease, and depression.
Paywalled Paper: Risk Factors for Young-Onset Dementia in the UK Biobank
Press report on this newly-published study:
