Rewriting the Rules of Longevity: Scientists Propose Alternative Connection Between Diet and Aging

#1
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#2

That theory would argue for more fermented milk products.

If one is not diabetic, honey is number 2, and dulce de leche is number 3. Lifeay kefir is fourth. The yogurt products have a bit less.

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#3

In other words, to simplify, substituting glucose (sugar) with galactose (honey) early in life?

#4

This paper refers to life long dietary protocols

“Crucially, the dietary change only works when cells are young, and actually diet makes little difference in old yeast….”

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#5

How does one define old yeast?

It is hard to translate what youth means between yeast and humans, but all these studies point to the same trend – to live a long and healthy life, a healthy diet from an early age makes a difference,” explains Dr. Houseley.

#6

I surely don’t know but I do know that I can’t go back in time. Fortunately, my mom made healthy meals and made me eat them when I was young. But I wrecked the s**t out of that trend in my 20s and 30s, mostly out of ignorance.

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#7

From what I’ve researched, it seems to be the opposite of a longevity-promoting diet.

Negative Effects of Galactose

Animal Models: Studies in rodents have demonstrated that high doses of galactose can induce pro-aging effects such as oxidative stress, inflammation, and cellular damage. This model has been used to study induced aging, where administering galactose at supranatural levels generates signs of premature aging.

Oxidative Stress: Galactose can increase the production of reactive oxygen species (ROS), which damage proteins, lipids, and DNA, contributing to cellular aging and age-related diseases.

Normal Consumption

In normal doses, such as those consumed in a balanced diet, galactose has not shown significant negative effects. In fact, it is present in breast milk, which is crucial for the early development of mammals.
However, milk is produced by nature to make calves grow quickly, and this growth stimulation also accelerates aging.

References:

  1. Song, X., Bao, M., Li, D., & Li, Y. M. (1999). Advanced glycation in D-galactose induced mouse aging model. Mechanisms of Ageing and Development, 108(3), 239-251.
  2. Cui, X., Zuo, P., Zhang, Q., Li, X., Hu, Y., Long, J., … & Liu, J. (2004). Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid. Journal of Neuroscience Research, 78(6), 797-805.
  3. Ho, S. C., Liu, J. H., & Wu, R. Y. (2003). Establishment of the mimetic aging effect in mice caused by D-galactose. Biological and Pharmaceutical Bulletin, 26(3), 354-360.
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