Very important to get checked for Factor V and Jak2 (I think there might be one other genetic clotting variant) on a basic blood test. Having these raises risk significantly.
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GLP1-Ra dose response.
Made this little graphic to help my clients understand that the dose is the key to success and to not worry about it being “too high”. It takes what it takes to get the job done. Lifestyle, sex, genetics, hormones, etc all have a part to play for each individual in how they respond to any given dose.
Each dose level will reach a state of homeostasis, at that point, either the weight loss goal has been reached or it hasn’t.
It’s also important to keep in mind that ALL the studies on weight loss with GLP1’s involve ramping up to the MAX dose as quickly as possible and running the studies for 3 to 5 years. People who expect the “magic needle” to do all the work at 1 or 2 non-MAX dose levels in 2 or 3 months are going to be disappointed. This does not mean people can’t achieve their goal at a lower dose, they just need to understand the process.
My wife and I are both excellent responders and achieved our goal with a “small” dose, I never went over 3.5 mg and neither did she, and we both maintain at a lower dose than that, 2.5 for her and 2.0 for me. We have a few people on 9mg per week who are maintaining at their idea weight. Still not quite at the MAX dose of 12mg for Reta.
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Some doctors have found microdosing Tirzepatide to be effective for some subtypes of Long Covid. They are dosing starting at 1/10 or 1/5 of the recommended initial starting dose for Mounjaro. There are warnings against microdosing using the bottled version. And concerns about compounded versions which I suspect are used by the Long Covid doctors. There are no Long Covid doctors that I can locate in my state using this approach. I’d appreciate any suggestions on usage and where to purchase. I am thinking about trying a GLP-1 instead which may be easier to microdosed using a click pen, but I’d rather use what is thought to be more effective.
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