Researchers studying 258 mammal species found that animals with an appendix live longer and suffer fewer severe diarrheal infections

The appendix is not a useless organ. For over a century it was seen as an evolutionary leftover, but recent studies challenge that idea.

Evolution: it appeared independently between 16 and about 30 times in mammals over 80 million years, suggesting survival value. Why some animals (cats, dogs, horses, whales) lack it remains a mystery.

Likely functions:

  • A refuge for beneficial gut bacteria, helping repopulate the intestines after severe diarrhea.
  • Lymphoid tissue (immune cells) that helps defend the body against pathogens.

Evidence (French team):

  • 2021 study: across 258 mammal species, those with an appendix live longer, probably due to lower mortality from infections.
  • 2023 study: across 1,251 primates, those with an appendix had less frequent and less severe diarrhea.
  • Caveat: the animals lived in a park, not in the wild.

Appendicitis: it is caused by a blockage and can lead to peritonitis, but it is much less common than the illnesses the appendix helps prevent. Surgery remains the treatment.

Conclusion: the appendix has a protective function and may contribute to longer lifespan.

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