Rapamycin, skin tags, and melanoma risks?

#1

Hello everyone!

I have been taking Rapamycin for about a year.

My dog is enrolled in a program to take it but I stopped it because she is a breed that is known to have very high instances of carcinogenic melanoma. If my reading is correct, Rapamycin can reduce non-carcinogenic melanomas but not metastatic ones. Is giving my dog Rapamycin to my dog a bad idea?

Secondly, my wife gets skin tags (acrochordons) and melanoma risk is supposedly not a correlated factor however, I thought I would ask here incase someone has seen any related information that might influence her decision to start rapamycin.

Thank you!!

#2

Regarding skin tags, I recommend you review this post: My DOG, My PARTNER, and ME: A Week by Week Rapalogue - #19 by RapAdmin

#3

Skin tags are benign growths that can be removed if desired. I doubt Rapa has any impact.
Melanoma is a serious skin cancer that is never benign. I doubt Rapa has any relation to causation.
There is no relationship between skin tags and Melanoma.

#4

If the rapa caused or worsened insulin resistance, it could in theory secondarily cause or exacerbate skin tags, but real-world significance unknown.

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