Maybe. According to the PEARL trial data, compounded rapamycin is approximately 1/3 of the serum value of the coated rapamycin. That would mean 45mg compounded translates to 15mg coated.
Thanks. I will bring that up to my doctor. btw, as a side noteā¦ I could easily put the pill in an āentericā capsule. Would that have the same effect?
There are mixed reports about that, centering on the claim that many commercially available āentericā coated shells are not in fact enteric in the sense that they pass through the stomach undissolved into the small intestine. But there are ones that supposedly do and are legit - there are threads about it somewhere on this site. In principle, rapamycin in such a legit shell should act just as an enteric coated one. Thatās the theory. Who knows what the reality is. For me, I take the rapamycin from Indian pharmacies two major brands Eris/Biocon or Zydus, and I have tested my blood levels of rapamycin 50 hours after a 6mg dose and both showed up robustly, thus telling me that whatever the coating on the two Indian brands, they are absorbed by my body well. Letās keep in mind that everyoneās absorption is slightly different, so you have to measure to know how it works for you. I take on an empty stomach, because I donāt want any confounders. YMMV.
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Enteric coating or stomach acid is not the issue, itās solubility.