Rapamycin and Atherosclerosis

An interesting new paper on how rapamycin may help prevent heart disease:

Therapeutic strategies associated with rapamycin have worked well in a number of different diseases, and there is every reason to believe that targeting components of the mTOR pathway may pay off in atherosclerosis as well.

This recent (summer last year) research out of Stanford U. seems to also suggest that rapamycin could be helpful:


mTOR inhibition: A promising strategy for stabilization of atherosclerotic plaques

A large body of evidence indicates that mammalian target of rapamycin (mTOR) inhibitors such as rapamycin or everolimus have pleiotropic anti-atherosclerotic effects so that these drugs can be used as add-on therapy to prevent or delay the pathogenesis of atherosclerosis.