Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2

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It’s worth thinking about, especially in the first couple of days after an intermittent dose. Most such doses are far below the daily doses for therapeutic immune suppression, and smaller doses might or might not increase entry into the cell.

Yeah, lately I had been feeling complacent thinking that rapamycin only causes issues with bacterial infections and not viral infections.

Wow, good to know! Thanks for posting that. Definitely argues for wearing a quality N95 mask or equivalent when around others, especially in the first few days after a dose.

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