Rapa and the effect it has on female hormones

Hello! I’m 47 and started Sirolimus on March 19. I take 3mg a week. I have more energy, workouts are like when I was in the 30’s, and my head is clearer. However, I’m experiencing very sore breasts/ nipples. Could it be perimenopause or the Rapa? Are there any articles/ science about what rapa does to the female hormones? Anyone else have this side effect?


This is an interesting question, following.
I am 44 and in early menopause, plan to start rapa soon.