This is very cool…
From Austin Argentieri, here: x.com
We developed a proteomic age clock that is associated with nearly all major chronic diseases, multimorbidity, mortality, and aging biomarkers (e.g., telomeres).
Importantly, we developed our proteomic age clock to have high generalizability to diverse populations. It predicts age with high accuracy in training data from uk_biobank (r=0.94), but also in independent validation data from China (r=0.92) and Finland (r=0.94).
Open Access Paper:
Anyone devolving it commercially / for direct to consumer?
I can see the immense usefulness of this blood test if standardised and commercialized - I sincerely hope this happens very soon. For one, we will be able to check if rapamycin is doing anything to change our proteomic profile. This is just one example. Of course that is only if the profile is changeable via pharmacology which I think can be one of the simplest new studies to conduct.
New article on this with an interview of Austin Argentieri:
https://hms.harvard.edu/news/gauging-biological-age-disease-risk-proteomic-clock
Though the test is currently restricted to the research lab, the team is working on developing it into something anyone can order at a doctor’s office.
