AnUser
January 19, 2024, 12:54am
#1
Try https://www.perplexity.ai/ for research, first impressions?
3 Likes
AnUser
January 19, 2024, 2:36am
#2
It helped me research lipophilic vs. hydrophilic statins, led me to a tangent on statins for Parkinson’s disease:
Continuation of lipophilic statins like atorvastatin is associated with decreased risk of Parkinson’s:
Results: Among the 43,810 statin initiators, the incidence rate for PD was 1.68 and 3.52 per 1,000,000 person-days for lipophilic and hydrophilic statins, respectively. Continuation of lipophilic statins was associated with a decreased risk of PD (hazard ratio [HR] 0.42 [95% confidence interval 0.27–0.64]) as compared with statin discontinuation, which was not modified by comorbidities or medications. There was no association between hydrophilic statins and occurrence of PD. Among lipophilic statins, a significant association was observed for simvastatin (HR 0.23 [0.07–0.73]) and atorvastatin (HR 0.33 [0.17–0.65]), especially in female users (HR 0.11 [0.02–0.80] for simvastatin; HR 0.24 [0.09–0.64] for atorvastatin). As for atorvastatin users, the beneficial effect was seen in the elderly subgroup (HR 0.42 [0.21–0.87]). However, long-term use of statins, either lipophilic or hydroph…
3 Likes
EnrQay
January 19, 2024, 2:18pm
#3
At first look, it looks very competitive with elicit.com , which I have used extensively. I like the feature tthat hey offers related questions. I’m going to sign up and compare the two sites.
2 Likes