I had a moderately serious car accident last week, four days after my usual 8mg dose.
I had some large 2nd degree burns (from side airbag!), and bad rib/chest soreness, but no worse for wear otherwise.
I have paused my dose for now. My burns have healed much faster than I would have expected.
How would you think about pausing Rapamycin during acute healing from mild trauma?
I was also interested in my differential CBC, which I’ve never had before. I had a higher percentage of Neutrophils verses Lymphocytes. I have to wonder if this is the immune system modulation from Rapamycin at play.
Probably not a bad idea to pause the rapamycin whenever you’re recovering from a wounding. The evidence is generally that at higher dosing, and continual dosing, that wound healing is slowed but its better safe than sorry.
Every type of intervention that inhibit mTOR, the anabolic processes, I would try to take a pause from or minimize. Interventions like extended fasting, time restricted eating, calorie restriction, rapamycin etc. I would also help the body to heal better and faster by for example increasing little bit the energy intake, protein intake, zinc, iron, vitamine C and also avoid dehydration. Take care my friend