Thanks for the clarification. While it’s true that people often have personal insights into their health, evidence can tell a different story. For instance, Dr. Green’s claims about rapamycin mitigating or treating COVID-19 haven’t been backed by strong evidence. Although he may have had positive personal experiences, larger-scale studies show no significant effect of rapamycin in preventing or treating COVID-19.
I have no idea what he said re: rapamycin and covid-19 but
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it has no bearing on his knowledge of his own physical state
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I’m not at all sure that randomized clinical trials invalidate his anecdotal observations, seeing as they might be following completely different protocols. You can see how issues re: ensuring the trial participants were blinded, necessitating using compounded rapa vs pills with enteric coating, already led to complications in the latest trial. So until I see the exact protocol used I will reserve judgment.
Rapamycin, an immunosuppressant drug, has been explored for its potential role in managing cytokine storms in viral infections, including COVID-19. Here are some key points about its role:
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Modulating Immune Response: Rapamycin works by inhibiting the mTOR (mechanistic target of rapamycin) pathway, which plays a crucial role in cell growth, proliferation, and immune response. By modulating this pathway, Rapamycin can potentially reduce the excessive immune response that leads to cytokine storms¹.
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Reducing Inflammation: Cytokine storms are characterized by an overproduction of pro-inflammatory cytokines, which can lead to severe tissue damage and complications like acute respiratory distress syndrome (ARDS). Rapamycin’s anti-inflammatory properties may help in reducing this excessive inflammation².
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Clinical Studies and Research: Some studies have suggested that Rapamycin could be beneficial in managing cytokine storms by dampening the hyperactive immune response. However, the evidence is still emerging, and more clinical trials are needed to confirm its efficacy and safety in this context¹².
Source: Conversation with Copilot, 10/6/2024
(1) COVID-19: from immune response to clinical intervention. COVID-19: from immune response to clinical intervention | Precision Clinical Medicine | Oxford Academic.
(2) COVID-19 infection: an overview on cytokine storm and related … COVID-19 infection: an overview on cytokine storm and related interventions | Virology Journal | Full Text.
(3) Harnessing the immune system to overcome cytokine storm and reduce … Harnessing the immune system to overcome cytokine storm and reduce viral load in COVID-19: a review of the phases of illness and therapeutic agents | Virology Journal | Full Text.
(4) Calming a cytokine storm - Nature. Calming a cytokine storm.
(5) Potential therapeutic approaches for targeted inhibition of … https://royalsocietypublishing.org/doi/pdf/10.1098/rsfs.2021.0006.
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source? curious which studies.
“The adequate levels of vitamin D in the host have been associated with the reduced release of proinflammatory cytokines, thus lowering the risk of a cytokine storm; increased levels of anti-inflammatory cytokines and enhanced secretion of natural antimicrobial peptides”
Above is from;
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Yikes, I am saddened to hear of Misha’s passing, In addition to being a prolific and articulate scientist, he was also very generous with his time. He offered me advice via emails on several rapamycin-related topics when I was writing my book Rapamycin, mTOR, Autophagy & Treating mTOR Syndrome. I am left with fond memories…!
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I wonder if Dr. B tried to use the combination of Ivermectin + Febendazole that has had great success with various types of cancer. Recommended by Dr. Makis from Canada and the FLCCC. I don’t know if anyone has had any experience using these generic medications to treat cancer.
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A great many people are using these. There are facebook groups etc… My daughter has cancer and she uses them. Has not needed chemo yet and seems pretty healthy. She does a lot of other stuff too. IV vitamin C and doxycycline. She has KRAS, which makes the vitamin C work better. There is no proof on these things, there are groups studying them but probably underfunded since it’s hard to make money on cheap old drugs.
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