LOL. What a simplistic view. Why is it, that I have had no pimples (not that surprising at age 67!), but started getting them when I took rapamycin? The one thing that we do know about rapamycin, is that it reliably suppresses mTOR. I don’t consume milk either.
I think this whole theory needs some refinement, because as it stands, it’s a mess.
How would reduced nutrient sensing increase IGF-1 levels? It’s literally the opposite high glycemic and protein diets cause the IGF-1 to increase.
If I had to guess why rapamycin would cause some Acne breakouts ( I get an occasional pimple after rapamycin as well) I would venture to say that it might have to do something with impaired immune response to topical pathogens or skin barrier function issues.