Well, here’s a paradox for you. I had lower BP on 20mg/day telmi than I have now on 40mg/day. Not huge, but definitely significant, about SBP 8 points and DBP 4 points - these are not fluke readings, I always take them at the same time with the same device, consistently. So who knows, maybe something else has changed, though I can’t think what that would be diet, exercise supplements all kept steady .
Another option…
Here’s the breakdown for telmisartan (Micardis and generics) and pill splitting:
1. Tablet formulation
- Telmisartan is supplied as film-coated tablets in fixed strengths (20 mg, 40 mg, 80 mg).
- The coating is not an extended-release or enteric-release technology; it is mainly to improve stability (telmisartan is moisture-sensitive).
- That means splitting does not destroy a time-release system — you still get the same pharmacokinetics.
2. Practicality of splitting
- The tablets are not scored, so breaking them may not give perfectly even halves.
- If you split them, you may see some crumbling, but the drug content should remain stable if consumed soon after.
- Because telmisartan is moisture-sensitive, storing split halves for long periods (weeks/months) is not ideal — the coating helps protect the active drug from degradation.
3. Dosing flexibility
- Clinically, many physicians do split telmisartan tablets (especially the 80 mg ones) to achieve intermediate doses like 40 mg or 20 mg at lower cost.
- Pharmacists often note that variability in split dose (±10–15%) is usually acceptable for blood pressure medications like ARBs, since dosing is titrated to effect and safety margins are wide.
4. Cost considerations
- In some markets, higher-strength tablets (e.g., 80 mg) cost the same as lower-strength ones. Splitting can therefore save money when prescribed by a doctor.
- Insurance and pharmacy policies may differ — sometimes the pharmacy benefit manager disallows splitting.
Bottom line:
Yes, telmisartan can generally be split without losing effectiveness, since it is not extended-release. The main issues are dose unevenness and stability after splitting. If you do it:
- Use a proper pill splitter, not a knife.
- Split only what you’ll use in the next few days to weeks (don’t store for months).
- Keep the halves in a dry, airtight container to limit moisture exposure.
Always confirm with your prescribing doctor or pharmacist, because local formulations and coatings can vary slightly.
Note, this may not be applicable to the telmisartan you buy from India. I bought 40mg pills Teleact Ranbaxy/Sun Pharma and they are indeed scored in the middle. Nonetheless it is very true they are moisture sensitive. Also, even though they are scored in the middle, splitting them is tricky, because they tend to crumble very easily, so you are left with two uneven “halves”, and some crumbs and powder. You have to use good splitting technique.
Thanks @RapAdmin I currently use the 40 mg tabs and split them to 20 mg. I like to save money on my daily meds.
Nice effect on adiponectin. The increase in adiponectin might be caused by telmisartan being a PPARgamma agonist but activation of PPARgamma can increase subcutaneous fat but reduce visceral fat and the reduction in visceral fat increases adiponectin.
High blood pressure affects more than a billion people worldwide and remains one of the leading drivers of heart, kidney and brain disease. In this episode, I sit down with Dr Raymond Townsend, Professor of Medicine and Director of the Hypertension Programme at the University of Pennsylvania, to uncover what truly causes blood pressure to rise, how it damages the body, and what steps can help reverse or prevent it. With more than four decades of clinical and research experience, Dr Townsend shares insights into the mechanisms of hypertension, the importance of early detection, and why empathy, consistency and accurate measurement matter as much as medication or diet. Together we explore how blood pressure control can protect vital organs, extend healthspan and reduce risk long before symptoms appear.
Interesting comments on Taurine and BP:
Taurine is the most underrated supplement when it comes to blood pressure, abundantly found in heart muscle tissue, modulates calcium handling, reduces sympathetic tone, and enhances nitric oxide.
Is the cuff charged or have fresh batteries?
It’s fully charged. I just used it tonight. The measurements were 123/69. It only goes into the high 90s when I take Telmisartan 20 mg. 123 is a little high, but it’s better than too low and passing out. I guess I’ll have to wait for my arteries to clog up more before taking Telmisartan.