Long-term NTP toxicology and carcinogenicity studies usually involve exposing laboratory animals (rats and mice) to a substance for a period of two years. These studies are designed and conducted to characterize and evaluate the toxicologic potential, including carcinogenic activity, of selected substances. Substances selected for NTP toxicology and carcinogenesis studies are chosen primarily on the basis of human exposure, level of production, and chemical structure. Substance selection is not an indicator of a substance’s carcinogenic potential.
The methods, results, and conclusions of these studies are published in NTP’s Technical Report (TR) series after undergoing peer review. The interpretive conclusions presented in Technical Reports and Abstracts are based only on the results of these NTP studies.
https://ntp.niehs.nih.gov/publications/reports/tr?type=Technical%20Report
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