NOVOS Core randomized, double-blind, placebo-controlled human clinical trial

You’re absolutely right. We shouldn’t rely on guesswork for anti-aging supplements,we need evidence-based testing

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Then yes, we agree and your product is a good example why combinations tend to work better as long as they make sense. The big question here is which specific ingredients are driving these positive benefits and would they still yield benefits if they weren’t combined with one another. I could only imagine the results of a double blind placebo controlled study with NAC, Astaxanthin (included in your protein bar but not Core), and taurine added to the product. There is more positive evidence in favor of those three since the product was formulated, while pterostilbene and fisetin don’t quite have the same positive reputation that they once had.

Hi, can NOVOS Core be taken together with Urolithin A? Will there be any interference or neutralizing effects between them?

Well, I am still very active and kicking at 85. I know I am an N=1 experiment. I have been practicing “poly pharma” since ~ 1995.

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At the risk of sounding critical, updating the formula to include things like astaxanthin, NAC, and taurine while removing pterostilbene, fisetin, and ginger root and switching the lithium from asparatate to orotate would make this a heck of an upgraded product. I can’t help but feel like the product is stuck in 2020 when it came out. I took it myself from 2020-2022 then decided I was better off with a handful of the ingredients while adding those things it didn’t include. Dr. Stanfield updates Microvitamin every few months after all.

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One option is to design your own formula.

https://getvitaminlab.com/

I’ve been curious about these services, but I’ve never heard about the quality of their sourcing. You?

The Future of Nutrition is Precision. The era of “one-size-fits-all” health is rapidly closing. While traditional supplement brands fill shelves with generic dosages designed for a statistical “average,” companies like VitaminLab are pioneering a shift toward Precision Nutrition. At the same time, companies like NOVOS are bringing academic rigor to the field by providing large-scale Randomized Controlled Trials (RCTs) to prove efficacy on a group level.

The future of the industry lies in moving beyond guesswork and into data-driven supplementation. Here is why personalized formulas are the next logical step in human optimization:

Every individual possesses a unique genetic blueprint that dictates nutrient metabolism. We can now analyze our DNA to identify specific markers—such as the MTHFR gene’s impact on folate absorption—allowing users to bypass biological bottlenecks. This shift enables personally trialed formulas that work with your DNA, rather than against it.

Personalization transforms supplements into a tool for proactive risk management. Instead of a “shotgun approach,” individuals can tailor their intake to address specific vulnerabilities—whether that is bone density, cognitive decline, or metabolic health. This ensures you are taking exactly what is required to mitigate your specific long-term health risks.

There is a massive chasm between merely avoiding deficiency and achieving optimal performance. Personalized supplements allow for high-precision dosing, ensuring active ingredients reach therapeutic levels without the toxicity risks or wasted capital associated with over-supplementing.

As the market matures, two dominant philosophies for proving value have emerged:

Approach Methodology Goal
Personalized (VitaminLab) Data-driven (Blood, DNA, Lifestyle) Individual Optimization: Solving for the unique “N-of-1.”
Evidence-Based (NOVOS) Group-level RCTs Proven Efficacy: Statistically significant results across populations.

The Future is Personal. While companies like NOVOS provide essential validation—proving that specific longevity molecules work on a general level—the ultimate application remains personal. Even a “proven” ingredient may be redundant if your body already produces enough of it or lacks the specific transporters to utilize it.

The Ultimate Lifestyle Hack: Complexity vs. Simplicity

For many in the health-optimization space, the current reality involves managing a cabinet of 50–60 individual pill bottles. We already measure our biology through wearable tech and blood tests; personalizing the actual “input” is the natural next step.

VitaminLab nad companies like that, represents an attractive option to simplify this complexity. Instead of an unmanageable morning ritual of dozens of capsules, you consolidate your entire data-backed stack into a single, streamlined formula. It’s the transition from being a “pill-sorter” to a precision-optimized individual.

I have not tried them yet. I am still a pill-sorter. But would love the simplicity.

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