Nicotine benefits?

Hi Everyone

I would be very grateful indeed for your thoughts about this.

Firstly, please note that this post is about pure uncombusted nicotine on its own without any of the other chemicals that are in cigarettes or vapes.

I recently watched a YouTube video by Thomas DeLauer in which he cautiously suggests that Nicotine might be good for longevity. The video is as follows:

I have also seen the following article that suggests that it may be a good treatment for long covid, ME/CFS and fibromyalgia:

The following two links suggest that nicotine may help with migraines:

https://www.reddit.com/r/migraine/comments/qlegx2/nicotine_aborts_my_migraines_anybody_else/

However, in contrast to the above information, I have also seen various papers that suggest that nicotine on its own can potentially lead the body’s cells down various cancer pathways.

The following is an example:

I actually suspect that the cancer risk for nicotine is very much dose dependent.

As I understand it (correct me if I am wrong), there are, broadly speaking, two ways in which a person can get cancer which are as follows:

  1. I don’t know for certain if this is true but a while ago, I read somewhere (I can’t remember where) that everyone actually always has at least a very tiny amount of cancer in them but the body has strong defence and repair mechanisms which are constantly keeping this very tiny amount of cancer under control so that it does not develop into full-blown cancer. This suggests that a person can get full-blown cancer if something goes wrong with their defence and repair mechanisms.

  2. I think the other way a person can get cancer is if something external (for example, a high dose of radiation) causes a too much DNA damage for their defence and repair mechanisms to be able to cope with it.

I might be wrong but if what I have said here is correct then that suggests to me that provided a person’s defence and repair mechanisms are in full working order then they are very unlikely to get full-blown cancer from only a very small dose of something potentially carcinogenic.

What do you all think of what I have said so far in this post?

Do you think that a single 7mg 24-hour nicotine patch counts as a “very small dose” in the context of what I have said above?

Has anyone ever got cancer from just a nicotine patch?

Thank you very much.

Kind regards

Tim

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You might consider tiptoeing into this minefield with much lower doses using nicotine lozenges. If you are looking for a boost / neurotrophic effect, I’d check out methylene blue.

I’m staying away from nicotine due to dependence effects and ½ life that forces you to into withdrawal while you sleep. This is what I’ve heard, plus I don’t need it (I use MB).

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Keep in mind, Nicotine is both addictive and poisonous.

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I don’t know which emoji to use for an eye roll, but pretend Im putting it here.

ME/CFS is a real condition (unless those afflicted are pretending that they cannot physically move). Vlad Vexler is someone I would unlikely place in “pretending” category who needs to huff O2 and who is laying down most of the time. M.E. - Vlad Vexler

Nicotine can probably be used responsibly (like one time a week), in a very small dose from a patch, as rapid absorption in other forms are more addictive. I would worry about BP increase.

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