1 Like
The paper: Vitamin B12 Supports Skeletal Muscle Oxidative Phosphorylation Capacity in Male Mice 2026
Cornell University + University of Alabama at Birmingham
Exposure to a−B-12 diet led to uracil accumulation in mtDNA and impaired maximal oxidative capacity in skeletal muscle. B-12 supplementation improved complex IV maximal capacity in gastrocnemius from aged mice, a model of age-related skeletal muscle decline.
2 Likes
For sure. We can probably make this case for many micro nutrients. However, too much B12 isn’t such a good thing. I aim to keep my level between 400-700 and make sure MMA and Homocysteine are good.
1 Like