New study suggesting that rapamycin could be helpful in improving egg quality for invitro-fertilization (oocytes are the cells in an ovary which may undergo meiotic division to form an ovum, a mature female reproductive cell, in a human or other animal, which can divide to give rise to an embryo, after fertilization):
Conclusion: Rapamycin at 10 nM could ameliorate the developmental competence and quality of in vitro maturation (IVM) oocytes of mice, mainly by improving the chromosome alignments. The inhibition of mTORC1 pathway, which involved in activating DNA damage repair-associated genes may act as a potential mechanism for oocyte quality improvement by rapamycin.