Double wood capsules are in mg of LiOrotate, not elemental Li according to the company. See my post here
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I asked the company a couple days ago, and they said it contains 5mg elemental lithium.
I just replied with a pointer to the Amazon review. Will update with any follow up.
Update:
Still insisting that it’s elemental lithium, even after pointing out the Amazon comment.
The COA from the product web page says 5mg lithium orotate, and the third party test just says ‘lithium’, so seems ambigous.
Just buy something else.
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Wild that even the supplement manufacturer’s customer support is confused about elemental lithium vs lithium orotate.
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If a company cannot answer basic questions about fundamental aspects of their product, but instead engages in a bunch of waffling, it’s time to look for a different product/company.
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If this is true at a minimum change the label to indicate 130 mg Li orotate, 5 mg elemental Li.
Nice discussion of rapamycin (04/11/25) courtesy of Dr. Fraser.
Is RAPAMYCIN the KEY to LONGER LIFE and Better Health? (DrApoE4)
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Thanks - took a while to get the files and then get them formatted. Dr. Barzilai and Dr. Zazala were on that panel, and it was a pleasure to meet them.
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I find the “by design” hypothesis compelling. It looks like the original ideal design is gradually eroded by cumulative damage, leading to a final outcome that may likely deviate from the designer’s intended goal. But what was the initial ideal blueprint if there was one at all? We cannot avoid damage unfortunately…
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I agree also that evolution selects for mean lifespan. This is very obvious when you look at different species. If people want I can give a link to one of my posts about this.
My own conclusion is that the aging and development clocks are the same clock. That is in my poster for BSRA again if people want the link to this again just ask.
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Yes, pls post the link.
This is the link which looks at evolution selecting for mean lifespan.
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There is always hope that if we can’t cure Alzheimer’s, at least little by little, we are reducing the per capita incidence.
Nick (PhD, Oxford; MD, Harvard) is one of my favorite YouTube MDs. His videos are a little shorter than most, and he is not always trying to sell anything or get you to upgrade to “Patreon,” ring that bell, etc.
He is personally interested in Alzheimer’s because he possesses two copies of the APOE4 gene variation.
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What oil is it? (20 chars)
lysophosphotydlcholine, probably spelled wrong. Krill oil is a pretty good source.
I take phosphatydlcholine off and on and he never said whether that would help, or if he did I did’t understand it.
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Krill oil--------------------------------------------
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So … I think the thing that seems to be clear is that individuals with ApoE4’s (especially homozygous) have real problems getting DHA into their brain (not EPA of which a small % will be converted to DHA).
If the DHA is phospholipid bound then it bypasses the defective receptor … thus an argument for NOT using standard fish oil capsules as they are stripped of their phospholipids. Krill is bound to phospholipids, but also has high risk of being rancid and actually being very hard to determine that it is rancid.
We then see a variety of DHA with phospholipids — and that makes individuals feel like they’ve solve the issue, but when one looks into almost all, they are just DHA/EPA with some mixed phospholipids, but the phospholipids are not actually bound to the DHA.
We know the fatty fish with plenty of Omega 3’s has most of the DHA phospholipid bound … so getting wild caught salmon (biggest fish I’d advise), mackerel, sardines is a good back up. Then I have my backup addition of Krill with the Naturebell product that has a fair bit in it. Amazon.com: Antarctic Krill Oil 2000mg Supplement, 240 Softgels, 3X Strength Natural Source of Omega-3s, EPA 240mg + DHA 160mg + Astaxanthin 800mcg – No Fishy Aftertaste – Mercury Free & Non-GMO : Health & Household
and I take a double dose as I’m trying to get close to 1000 mg of Omega 3’s per day between this and fish.
There are all types of fancy and expensive options out there … this is my current strategy, but it continues to evolve and next month I might change to something different.
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That is true, but:
“Krill are processed quickly on board factory ships in cold Antarctic waters, often within hours of harvest, which reduces pre-extraction spoilage.”
And krill oil contains astaxanthin, an antioxidant, which makes krill oil red and generally gives it a longer shelf life. However, I can’t find any good papers that provide a controlled comparison. i.e., date manufactured, constant temperatures, etc.
But my guess is krill oil has a better shelf life than fish oil, if only because it seems a little more direct to the consumer.
Two brands that were tested; there may be others equally as good:
Kori Pure Antarctic Krill Oil 1200 mg (Labdoor test page): Tested 2025.
Labdoor
Viva Naturals Antarctic Krill Oil (Labdoor test page): PV 1.53 mEq/kg (well below PV 5 limit). Tested Feb 2025.
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So you take 4 softgells correct? Do you worry about increased atrial fibrillation risk?
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The total DHA+EPA is 4 softgels is slightly under 1000 mg and at least in the review I read - it was only in doses significantly over 1 gram of DHA/EPA that we saw excess in AF.
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Are we sure that phospholipid form (Krill Oil) has better absorption/diffusion across the BBB? I only looked at 1 review paper from 2020, but that review basically states that Krill oil has better bioavailability across enterocytes and is broken down into FFA and incorporated into micelles in the GI tract. That’s what I would expect. Doesn’t sound like a phospholipid/fatty acid is absorbed intact into the plasma. The studies they reviewed show either equal plasma/brain levels with KO vs FO, or higher levels with KO which you could easily overcome by taking higher doses of fish oil (cheaper). Just curious because I’ve never looked into it before.
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