mTORC1 in energy expenditure: consequences for obesity | Nature Reviews Endocrinology

#1

https://www.nature.com/articles/s41574-023-00934-0

Can anyone get this from behind the paywall?

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#2

Interesting, including:

  • mTORC1 activation is required for central sympathetic nervous system (SNS) stimulation and SNS effects on white adipose tissue (WAT), brown adipose tissue (BAT) and skeletal muscle, which lead to WAT browning and increased energy expenditure.
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#3

Yes, this adds a new dimension to my appreciation of mtor.

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